Enzymatic conversion of DL-.ALPHA.-amino-.EPSILON.-caprolactam into L-lysine. II. Hydrolysis of L-.ALPHA.-amino-.EPSILON.-caprolactam by yeasts.
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چکیده
منابع مشابه
Amino-caprolactam derivatives as gamma-secretase inhibitors.
A series of amino-caprolactam sulfonamides were developed from a screening hit. Compounds with good in vitro and in vivo gamma-secretase activity are reported.
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The c o n d e n s a t io n o f racemic ly s in e to p o ly -D L ly s in e produces a great number o f d is t in guishable molecules. Following merely statistical reasoning the number o f “pure peptides“ — consisting of only one sort of enantiomers — should be extremely low. The hydrolysis of polyD L -ly s in e by pronase a n d t a k a -d ia s ta s e shows that a content of about 3% “pure“ pol...
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Addition of Potassium cyanide to a mixture of Schiff base and lithium perchlorate afforded a-aminonitriles in high yields. Addition of potassium cyanide to a methanolic solution of Schiff base and phosphoric acid afforded a-aminonitriles. When the reaction mixture was refluxed it gave a-amino acids in high yields.
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In spite of its clinical and nutritional importance, l-alanyl-l-glutamine (Ala-Gln) has not been widely used due to the absence of an efficient manufacturing method. Here, we present a novel method for the fermentative production of Ala-Gln using an Escherichia coli strain expressing l-amino acid alpha-ligase (Lal), which catalyzes the formation of dipeptides by combining two amino acids in an ...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1976
ISSN: 0002-1369,1881-1280
DOI: 10.1271/bbb1961.40.1695